د ستافیلوکوکس اوریوس باکتریا ناروغیو ته کتنه او د هغه د مخنیوۍ لارې چارې

Abstract

ABSTRACT

Staphylococcus aureus is a Gram-positive, opportunistic, and pathogenic bacterium that poses a serious threat to human health, particularly methicillin-resistant strains (MRSA). The objective of this study is to evaluate the clinical significance of S. aureus, its patterns of antibiotic resistance, and the effectiveness of preventive strategies. For this purpose, a systematic review of recently published peer-reviewed international articles was conducted, alongside an assessment of relevant clinical reports and healthcare guidelines. The findings demonstrate that S. aureus is responsible for a wide spectrum of infections, ranging from superficial skin lesions to pneumonia, endocarditis, and sepsis. The emergence of resistance, especially against methicillin and other antibiotic classes, represents a major global health challenge. Evidence indicates that the principal transmission routes involve direct contact, contaminated instruments, and insufficient infection control measures within healthcare facilities. Preventive strategies emphasize strict adherence to hygiene protocols, regular handwashing, prudent antibiotic use, and continued research into novel antimicrobial agents. The overall results underscore that effective control of S. aureus requires a coordinated approach combining preventive measures, public awareness, and the development of innovative therapeutic interventions.

Keywords: Resistance Mechanisms, Staphylococcus aureus, Methicillin, Virulence Toxins